PARP3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Human cerebrum tissue lysate IHC: 20-100 Positive control: Human gastric cancer Predicted cell location: Cytoplasm or Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PARP3
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	poly(ADP-ribose) polymerase family member 3
Database Link	NP_005476 Entrez Gene 10039 Human UniProt ID Q9Y6F1
Background	The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	ADPRT3; ADPRTL2; ADPRTL3; ARTD3; IRT1; PADPRT-3
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Base excision repair

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