TMPRSS4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: A431 cells IHC: 30-150 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human TMPRSS4
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	48 kDa
Gene Name	transmembrane protease, serine 4
Database Link	NP_899070 Entrez Gene 214523 MouseEntrez Gene 56649 Human UniProt ID Q9NRS4
Background	This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	membrane-type serine protease 2; MT-SP2; serine 4; TMPRSS3; transmembrane protease; transmembrane serine protease 3; type II membrane serine protease
Reference Data
Protein Families	Druggable Genome, Protease, Transmembrane

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