TRAFD1 Rabbit Polyclonal Antibody
CAT#: TA349448S
Rabbit Polyclonal Anti-TRAFD1 Antibody
Size: 100 ul
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 200-1000 WB positive control: Mouse spleen tissue IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human TRAFD1 |
Isotype | IgG |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 65 kDa |
Gene Name | TRAF-type zinc finger domain containing 1 |
Database Link | |
Background | The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. |
Synonyms | FLN29 |
Reference Data |
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