EIF4E Rabbit Polyclonal Antibody
CAT#: TA327306S
Rabbit anti-EIF4E Polyclonal Antibody
Size: 100 ul
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CNY 800.00
货期*
2周
规格
Specifications
Product Data | |
Applications | ELISA, ICC/IF, IHC, IP, WB |
Recommend Dilution | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 25kDa |
Gene Name | eukaryotic translation initiation factor 4E |
Database Link | |
Background | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. |
Synonyms | AUTS19; CBP; eIF-4E; EIF4E1; EIF4EL1; EIF4F |
Reference Data | |
Protein Pathways | Insulin signaling pathway, mTOR signaling pathway |
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