ABCE1 Rabbit Polyclonal Antibody
CAT#: TA323290S
Anti-ABCE1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 3080.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: NIH/3T3 and SKOV3 cells, human ovarian cancer tissue |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 345-562 amino acids of human ATP-binding cassette, sub-family E (OABP), member 1 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 67 kDa |
| Gene Name | ATP binding cassette subfamily E member 1 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor; this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system; the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. |
| Synonyms | ABC38; OABP; RLI; RNASEL1; RNASELI; RNS4I |
| Reference Data | |
| Protein Families | Druggable Genome |
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