ICAD (DFFA) Rabbit Polyclonal Antibody

CAT#: TA322748S

Anti-DFFA Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



Need it in bulk or conjugated?
Get a free quote

CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1, 20 µg
    • 20 ug

CNY 2,900.00
CNY 6,650.00


Transient overexpression lysate of DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: Jurkat cell lysate
IHC: 30-150
Positive control: Human esophagus cancer
Predicted cell location: Nucleus and Cytoplasm
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to N terminal 269 amino acids of human DNA fragmentation factor, 45kDa, alpha polypeptide
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name DNA fragmentation factor subunit alpha
Background Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB; the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.?
Synonyms DFF-45; DFF1; ICAD
Reference Data
Protein Pathways Apoptosis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...