ICAD (DFFA) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5C4]

CAT#: TA500062AM

DFF45 (ICAD) mouse monoclonal antibody, clone OTI5C4 (formerly 5C4), Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI5C4" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Recombinant protein of human DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1, 20 µg
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Transient overexpression lysate of DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1
    • 100 ug

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Specifications

Product Data
Clone Name OTI5C4
Applications IF, WB
Recommend Dilution WB 1:2500~5000, IF 1:50~100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human DFFA (NP_004392) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 36.3 kDa
Gene Name DNA fragmentation factor subunit alpha
Background Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Synonyms DFF-45; DFF1; ICAD
Reference Data
Protein Pathways Apoptosis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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