GRB10 Rabbit Polyclonal Antibody
CAT＃: TA322628S
Anti-GRB10 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 1280.00
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CNY 3080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 10-50 Positive control: Human tonsil Predicted cell location: Cytoplasm, Cell membrane |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 38-51 amino acids of Human growth factor receptor-bound protein 10 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | growth factor receptor bound protein 10 |
| Database Link | |
| Background | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner; with expression observed from the paternal allele in the brain; and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Synonyms | Grb-10; GRB-IR; IRBP; MEG1; RSS |
| Reference Data | |
| Protein Families | Druggable Genome |
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