NTAL (LAT2) Rabbit Polyclonal Antibody
CAT#: TA322392S
Anti-LAT2 Rabbit Polyclonal Antibody
Size: 100 ul
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Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 10-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 27-243 amino acids of human linker for activation of T cells family, member 2 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | linker for activation of T-cells family member 2 |
| Database Link | |
| Background | This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome; a multisystem developmental disorder. This gene consists of at least 14 exons; and its alternative splicing generates 3 transcript variants; all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. |
| Synonyms | HSPC046; LAB; NTAL; WBSCR5; WBSCR15; WSCR5 |
| Reference Data | |
| Protein Families | Transmembrane |
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