RAD52 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 361-374 amino acids of Human RAD52 homolog (S. cerevisiae)
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	RAD52 homolog, DNA repair protein
Database Link	NP_602296 Entrez Gene 5893 Human UniProt ID P43351
Background	The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52; a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends; and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51; which suggested its role in RAD51 related DNA recombination and repair.
Synonyms	RP11-359B12.2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Homologous recombination

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