HMG1 (HMGB1) Rabbit Polyclonal Antibody
CAT＃: TA321436S
Anti-HMGB1 Rabbit Polyclonal Antibody
Size: 100 ul
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Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 10-50 Positive control: Human ovarian cancer Predicted cell location: Nucleus |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 167-181 amino acids of Human high mobility group box 1 |
| Isotype | IgG |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | high mobility group box 1 |
| Database Link | |
| Background | DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells |
| Synonyms | HMG1; HMG3; SBP-1 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Base excision repair |
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