TCTP (TPT1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 - 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Rabbit polyclonal TPT1 antibody was raised against a 19 amino acid peptide near the center of human TPT1.
Isotype	IgG
Formulation	TPT1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TPT1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	19 kDa
Gene Name	tumor protein, translationally-controlled 1
Database Link	NP_003286 Entrez Gene 22070 MouseEntrez Gene 116646 RatEntrez Gene 7178 Human UniProt ID P13693
Background	TPT1 Antibody: TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer’s disease and Down syndrome.
Synonyms	HRF; p02; p23; TCTP
Reference Data

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