CPEB1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CPEB1 antibody was raised against a 14 amino acid peptide from near the amino terminus of human CPEB1.
Isotype	IgG
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Affinity chromatography purified via peptide column
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	cytoplasmic polyadenylation element binding protein 1
Database Link	NP_001073001 Entrez Gene 12877 MouseEntrez Gene 293056 RatEntrez Gene 64506 Human UniProt ID Q9BZB8
Background	CPEB1 is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly(A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF)-1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist.
Synonyms	CPE-BP1; CPEB; CPEB-1; h-CPEB; hCPEB-1
Reference Data
Protein Pathways	Dorso-ventral axis formation, Oocyte meiosis, Progesterone-mediated oocyte maturation

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