CD177 Mouse Monoclonal Antibody [Clone ID: MEM-166]

Specifications

Product Data
Clone Name	MEM-166
Applications	FC, IP, WB
Recommend Dilution	Western Blot (Non-Reducing Conditions). Immunoprecipitation. Flow Cytometry: 1 µg/ml.
Reactivity	Human, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Granulocytes
Specificity	This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.
Isotype	IgG1
Formulation	PBS State: Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	CD177 molecule
Database Link	Entrez Gene 57126 Human UniProt ID Q8N6Q3
Background	CD177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kDa protein, 14 kDa greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97% of the caucasian population.
Synonyms	NB1, PRV1, HNA-2a, HNA2a
Reference Data

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