Cytokeratin 8 (KRT8) (+ KRT18/19) Mouse Monoclonal Antibody [Clone ID: 2A4]

Specifications

Product Data
Clone Name	2A4
Applications	IHC, WB
Recommend Dilution	Western blotting: at least 1/1000 dilution. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This antibody is reported to work at 1/100 dilution.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Cytokeratins isolated from cultured pig kidney epithelial cells. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
Specificity	The antibody recognizes cytokeratin nos. 8, 18 and 19 typical for simple epithelial cells.
Isotype	IgG1
Formulation	PBS State: Purified State: Liquid purified IgG fraction Stabilizer: 1.0% BSA Preservative: 0.09 % Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	keratin 8
Database Link	Entrez Gene 3856 Human UniProt ID P05787
Background	Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1, CK2, CK3, CK4, CK5, CK6, CK7, CK8 and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10, CK12, CK 13, CK14, CK16, CK17, CK18, CK19 and CK20.
Synonyms	KRT8, CYK8, Cytokeratin-8, CK8, Keratin-8, K8, Cytokeratin endo A
Reference Data

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