ENPP3 Mouse Monoclonal Antibody [Clone ID: NP4D6]

Specifications

Product Data
Clone Name	NP4D6
Applications	FC, IF
Recommend Dilution	Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	HEK-293 cells transfected with human CD203c
Specificity	This antibody reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
Isotype	IgG1
Formulation	Phosphate buffered saline (PBS) Label: APC State: Liquid Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: Containing 15 mM sodium azide
Conjugation	APC
Storage Condition	Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	ectonucleotide pyrophosphatase/phosphodiesterase 3
Database Link	Entrez Gene 5169 Human UniProt ID O14638
Background	CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.
Synonyms	E-NPP 3, PDNP3, Phosphodiesterase I beta, PD-I beta
Reference Data

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