FOXO1 Human siRNA Oligo Duplex (Locus ID 2308)
CAT#: SR320177
FOXO1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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SR320177 is the updated version of SR301618.
                
                
            CNY 4090.00
货期*
                        4周
                    规格
                        | Cited in 2 publications. | 
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                Specifications
| Product Data | |
| Purity | HPLC purified | 
| Quality Control | Tested by ESI-MS | 
| Sequences | Available with shipment | 
| Stability | One year from date of shipment when stored at -20°C. | 
| # of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). | 
| Note | Single siRNA duplex (10nmol) can be ordered. | 
| Reference Data | |
| RefSeq | NM_002015 | 
| Synonyms | FKH1; FKHR; FOXO1A | 
| Components | FOXO1 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 2308)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml | 
| Summary | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008] | 
| Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).  | 
        
Citations (2)
| The use of this RNAi has been cited in the following citations: | 
|---|
| 
                                                c‑Jun and FOXO1 mediate the expression of oncogenic PKC‑ι in human prostate cancer cells with an interplay between NF‑κB, IL‑8 and ICAM‑1
                                                ,RATNAYAKE, W;APOSTOLATOS, C;BREEDY, S;ACEVEDO‑DUNCAN, M;,
                                                World Acad Sci J
                                                
                                                [FOXO1]
                                                 | 
                                        
| 
                                                FOXO1 regulates oncogenic PKC-ι expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation
                                                ,Ratnayke, W;Apostolatos, C;Breedy, S;Apostolatos, A;Acevedo-Duncan, M;,
                                                wasj
                                                
                                                [FOXO1]
                                                 | 
                                        
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