LC3B (MAP1LC3B) Human siRNA Oligo Duplex (Locus ID 81631)
CAT#: SR313079
MAP1LC3B (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4090.00
货期*
                        4周
                    规格
                        | Cited in 1 publication. | 
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                Specifications
| Product Data | |
| Purity | HPLC purified | 
| Quality Control | Tested by ESI-MS | 
| Sequences | Available with shipment | 
| Stability | One year from date of shipment when stored at -20°C. | 
| # of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). | 
| Note | Single siRNA duplex (10nmol) can be ordered. | 
| Reference Data | |
| RefSeq | NM_022818 | 
| Synonyms | ATG8F; LC3B; MAP1A/1BLC3; MAP1LC3B-a | 
| Components | MAP1LC3B (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 81631)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml | 
| Summary | The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008] | 
| Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).  | 
        
Citations (1)
| The use of this RNAi has been cited in the following citations: | 
|---|
| 
                                                The apoptotic effect of 1'S-1'-Acetoxychavicol Acetate (ACA) enhanced by inhibition of non-canonical autophagy in human non-small cell lung cancer cells
                                                ,Sok, SP;Arshad, NM;Azmi, MN;Awang, K;Ozpolat, B;Hasima Nagoor, N;,
                                                PLoS ONE
                                                ,PubMed ID 28158287
                                                [MAP1LC3B]
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