Nucleotide binding protein like (NUBPL) Human siRNA Oligo Duplex (Locus ID 80224)
CAT#: SR312854
NUBPL (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4090.00
货期*
7周
规格
Cited in 2 publications. |
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Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001201573, NM_001201574, NM_025152, NR_120408 |
Synonyms | C14orf127; huInd1; IND1; MC1DN21 |
Components | NUBPL (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 80224)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. Mutations in this gene cause mitochondrial complex I deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
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Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1
,null,
Genome Medicine
,PubMed ID 35042540
[NUBPL]
|
Gene expression profiling of hypertrophic cardiomyocytes identifies new players in pathological remodelling
,null,
Cardiovascular Research
,PubMed ID 32717063
[NUBPL]
|
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