CDON Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Asp26-Pro943
Tag	C-His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Note	Recombinant Human Cell Adhesion Molecule-related/down-regulated by Oncogenes is produced by our Mammalian expression system and the target gene encoding Asp26-Pro943 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	50937
UniProt ID	Q4KMG0
Synonyms	Cell adhesion molecule-related/down-regulated by oncogenes; CDON; CDO
Summary	CDO (CAMrelated/down-regulated by oncogenes) is a member of the Immunoglubulin (Ig) superfamily, Ig/Fibronectin (FN) type III repeat family of cell surface proteins. Human CDO is a type I transmembrane (TM) glycoprotein. It is synthesized as a 1287 amino acid (aa) precursor that contains a 25 aa signal sequence, a 938 aa extracellular domain (ECD), a 21 aa TM segment and a 303 aa cytoplasmic region. The ECD contains five C2-type Iglike domains, followed by three FN type III repeats. The ECD of human CDO is 85% aa identical to mouse CDO ECD. CDO is found on muscle precursor and neural progenitor cells of the embryo. It likely promotes muscle differentiation, and contributes to axon guidance and neuronal patterning.
Protein Families	Transmembrane

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