Il2rb Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ala27-Glu240
Tag	C-hFc
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note	Recombinant Mouse Interleukin-2 Receptor subunit beta is produced by our Mammalian expression system and the target gene encoding Ala27-Glu240 is expressed with a hFc tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	16185
UniProt ID	P16297
Synonyms	Interleukin-2 receptor subunit beta; IL2RB; IL-2 receptor subunit beta; IL-2R subunit beta; High affinity IL-2 receptor subunit beta; CD122
Summary	IL-2RB, also known as interleukin-2 receptor subunit beta, is the receptor for interleukin-2, which plays a role in regulating normal lymphocyte development. IL-2RB expression was restricted to the earliest B22+ cells (CD43+CD24-; prepro B cells; fraction A) that proliferate vigorously to IL-2 in the absence of any stromal cells, but not to IL-15. IL2 receptor complex facilitates the receptor-mediated endocytosis and transduces the mitogenic signals of IL2. IL-2RB is the subunit that is critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase.

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