Il17f Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) R29-A161
Tag	C-8His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note	Recombinant Mouse Interleukin-17F is produced by Human 293 Cells. The target gene encoding R29-A161 is expressed with a 8His tag at the C terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	257630
UniProt ID	Q7TNI7
Summary	Interleukin-17F (IL-17F) is a secreted disulfide-linked homodimer that belongs to the IL-17 family. IL-17F is expressed in activated CD4+ T-cells and activated monocytes. IL-17 is commonly associated with allergic responses. It mediates the induction of neutrophilia in the lungs and the exacerbation of antigen-induced pulmonary allergic inflammation. IL-17 stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. It is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.

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