IL2 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) A21-T153
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note	Recombinant Human Interleukin-2 is produced by Human 293 Cells. The target gene encoding A21-T153 is expressed with a 6His tag at the C terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	3558
UniProt ID	P60568
Synonyms	Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2
Summary	Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system, and belongs to the IL-2 family. It is a leukocytotrophic hormone that is instrumental in the body's natural response to microbial infection and in discriminating between foreign (non-self) and self. IL-2 is also a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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