PRPS2 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Leu318
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of 2umM PB, 15umM NaCl, pH 7.4
Note	Recombinant Human PRPS2 is produced by E. coli. The target gene encoding Met1-Leu318 is expressed with a 6His tag at the C terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	5634
UniProt ID	P11908
Synonyms	Ribose-Phosphate Pyrophosphokinase 2; PPRibP; Phosphoribosyl Pyrophosphate Synthase II; PRS-II; PRPS2
Summary	Ribose-Phosphate Pyrophosphokinase 2 (PRPS2) is a phosphoribosyl pyrophosphate synthetase that belongs to the ribose-phosphate pyrophosphokinase family. PRPS2 is a homodimer. The active form could be a hexamer composed of three homodimers. PRPS2 catalyzes the synthesis of phosphoribosyl pyrophosphate (PRPP) that is essential for nucleotide synthesis. PRPS2 catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. In addition, PRPS2 plays a central role in the synthesis of purines and pyrimidines. Thus, dysfunction of the enzyme would undermine purine metabolism.
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Pentose phosphate pathway, Purine metabolism

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.