TNF alpha (TNF) Human Recombinant Protein
CAT#: TP723983
Human TNF alpha Protein, His Tag
View other "TNF alpha" proteins (11)
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CNY 5249.00
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence |
TNFα(Val77-Leu233)+6×His tag
|
| Tag | C-6×His |
| Predicted MW | 18.1 kDa |
| Purity | > 95% |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Preparation | Affinity purification |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Reference Data | |
| Locus ID | 7124 |
| UniProt ID | P01375 |
| Summary | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
| Protein Families | Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane |
| Protein Pathways | Adipocytokine signaling pathway, Allograft rejection, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Asthma, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Fc epsilon RI signaling pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Natural killer cell mediated cytotoxicity, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus, Type II diabetes mellitus |
Documents
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Resources
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC424626 | TNF HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY424626 | Transient overexpression lysate of tumor necrosis factor (TNF superfamily, member 2) (TNF) |
CNY 3080.00 |
|
| PH306983 | TNF MS Standard C13 and N15-labeled recombinant protein (NP_000585) |
CNY 19520.00 |
|
| TP306983 | Recombinant protein of human tumor necrosis factor (TNF superfamily, member 2) (TNF), 20 µg |
CNY 2900.00 |
|
| TP700015 | Recombinant protein of human soluble form of TNF-alpha with His and DDK tags, expressed in human cells |
CNY 6650.00 |
|
| TP720007 | Recombinant protein of human tumor necrosis factor (TNF superfamily, member 2) (TNF), the soluble form (Val77 -Leu233) |
CNY 3140.00 |
|
| TP721024 | Purified recombinant protein of Human tumor necrosis factor (TNF) |
CNY 1800.00 |
|
| TP721025 | Purified recombinant protein of Human tumor necrosis factor (TNF) |
CNY 1800.00 |
|
| TP723708 | Purified recombinant protein of Human tumor necrosis factor (TNF) |
CNY 4090.00 |
|
| TP750007 | Recombinant protein of human Tumor Necrosis Factor-a (TNFa) produced in E. coli. |
CNY 2040.00 |
|
| TP750117 | Purified recombinant protein of Human tumor necrosis factor (TNF) mutant, tag free, expressed in E.Coli, 50 ug |
CNY 2040.00 |
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