PDGF Receptor beta (PDGFRB) (NM_002609) Human Recombinant Protein
CAT＃: TP700117
Purified recombinant protein of human platelet-derived growth factor receptor, beta polypeptide(PDGFRB), with C-terminal DDK/His tag, expressed in human cells, 20 µg
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CNY 6650.00
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC600017, encoding the region (Leu33 – Val532) of human PDGFRB
|
| Tag | C-DDK/His |
| Predicted MW | 59 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | PBS, pH 7.4, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_002600 |
| Locus ID | 5159 |
| UniProt ID | P09619 |
| Refseq Size | 5718 |
| Cytogenetics | 5q32 |
| Refseq ORF | 3122 |
| Synonyms | CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT |
| Summary | The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017] |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton |
Documents
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400921 | PDGFRB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400921 | Transient overexpression lysate of platelet-derived growth factor receptor, beta polypeptide (PDGFRB) |
CNY 3080.00 |
|
| PH306377 | PDGFRB MS Standard C13 and N15-labeled recombinant protein (NP_002600) |
CNY 19520.00 |
|
| TP306377 | Recombinant protein of human platelet-derived growth factor receptor, beta polypeptide (PDGFRB), 20 µg |
CNY 2900.00 |
|
| TP710136 | Recombinant protein of human platelet-derived growth factor receptor, beta polypeptide (PDGFRB), residues 33-532aa, with C-terminal DDK tag, expressed in sf9, 20ug |
CNY 4020.00 |
|
| TP720649 | Purified recombinant protein of Human platelet-derived growth factor receptor, beta polypeptide (PDGFRB) |
CNY 1800.00 |
|
| TP723757 | Purified recombinant protein of Human platelet-derived growth factor receptor, beta polypeptide (PDGFRB / PDGF-BB) |
CNY 4090.00 |
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