Klhl42 (NM_001081237) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR224861 protein sequence Red=Cloning site Green=Tags(s) MSAEEMVQIRLEDRCYPVSKSKLIEQSDYFRALYRSGMREAVRPEVGPEVQQLRGLSAPGLRLVLDFINA GGAREGWGLSEDELAEASVLSEMVEAASFLQVTALLRLLLSHVRLGNCLELYRLAQVYGLPDLQDACLRF MVLRFHQVLCQPQFPLLLSPPQAPGDCSLKQRLREARMRGTPVLVALGDFLGGPLAPHPYQGEPPSMLRY EETTERWFPLANNLPPDLVNVRGYGSAILDNYLFIVGGYRITSQEISAAHSYNPITNEWLQVASMNQKRS NFKLVAVNSKLYAIGGQAVSNVECYNPEQDAWNFVAPLPNPLAEFSACECKGKIYVIGGYTTRDRNMNIL QYCPSADLWTLFETCDVHIRKQQMVSVEETIYIVGGCLHELGPNRRSSQSEDMLTVQSYNTVTRQWLYLK ENTSKSGLNLTCALHNDGIYIMSRDVTLSTSLEHRVFLKYNIFADSWEAFRRFPAFGHNLLISSLYLPNK AET SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	55.6 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001074706
Locus ID	232539
UniProt ID	Q8BFQ9
Refseq Size	6571
Cytogenetics	6 G3
Refseq ORF	1479
Synonyms	A330079N23Rik; AI450355; C230080I20Rik; Ctb9; Klhdc5; mKIAA1340
Summary	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis (By similarity).[UniProtKB/Swiss-Prot Function]

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