Gpatch3 (NM_172876) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR220777 representing NM_172876 Red=Cloning site Green=Tags(s) MASPRELDEESPVYLVVSGIPAVLRSAQLRSYFSQFREQRGGGFLCFHYRHRPERGPPQASPEAARAGPD PAAEDPVLAQAPASDARAVRARGSAAAQTRTCCCVVSVRGAAQAQRLLRMYSGRRWLDSQGTWLPGRCLI RRLRLPTEVSDLGSFPFKTRKELQSRRAENEAFTLADLKQLPELNPPVLMPNGNVGTPLRVFLELIRSCR LPPRIITQLQLQFPKTGSSRRYGNVPFLYEDSETVEQEEHVYTAEGEEIPQGSCSEDPAAGSFDEPEDEG QQQEEEEESGSEEDDDRGEEWERHEALHEDVTGQERTTERLFEEEIELKWEKGGSGLVFYTDAQFWQEEE GDFDEQTADDWDVDMSVYYDRDGGDKDARDSVQMRLERRLREGQEDGSVLGGQVGTFERHTKGIGRKVME RQGWAEGQGLGSRCSGVPEALDGDGQHPRCKRGLGYHGEKLQPFRQLKRPRRTGLGLISTIYDEPLPQDQ GETLLRRQPPTSMKFRTDMTFVKGSSCALDRPEPE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	59.2 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_766464
Locus ID	242691
UniProt ID	Q8BIY1
Refseq Size	2003
Cytogenetics	4 D2.3
Refseq ORF	1575
Synonyms	D930035B09Rik; Gpatc3
Summary	Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.