Fnip2 (NM_001162999) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR217038 representing NM_001162999 Red=Cloning site Green=Tags(s) MAPTLLQKLFNKRGGGAASAQARPPKEEPAFSWSCSEFGLSDIRLLVYQDCERRGRQVMFDSRAVQKMEE AAAQKAEDVPIKMSARCCQESSSSSGSSSSGSSSSHGFGGSLQHAKQQLPKYQYTRPASDVSMLGEMMFG SVAMSYKGSTLKIHYIRSPPQLMISKVFSATMGSFCGSTNNLQDSFEYINQDPQAGKLNTNQYNLGPFRT GSNLAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIFP RRSTDETFSLAEETCSSNPAMVRRKKIAISIIFSLCEREAAQRDFQDFFFSHFPLFESHMNRLKGAIEKA MISCRKISESSLRVQFYVSRLMEALGEFRGTIWNLYSVPRIAEPVWLTMMSNTLEKNQLCQRFLKEFILL IEQVNKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQSVNMLAKTHPYNPLWAQLGDLYGA IGSPVRLTRTVVIGKQKDLVQRILYVLTYFLRCSELQENQLSWSGNPSEDDQVINGSKIITALEKGEVEE SEYVVVTVSSEPALVPPILPQGTAERRSPEPTVVAEISEGVNTSELGHKPEKNRCKRPEQNSEASSMGFQ EAEPDSSWIPQGIFCEDKQNDQEATQDCSSSPPSCEVPRVRRRMDQQTLHSKLHGETLKKRAEQSAAWPC PDRHSQEDPPVEKVTFHIGSSISPESDFESRTKRMEERLKACGHFHGASASASSSMDTGLTQEQQGSGCS FKADFEKDITPQDHSSGGEGVSEDRGLRANMTHAVGQLSQVDGPLAHSLCAAESGRRLLEQTRDVQLKGY KGPSSEPVPNRCRQQGGLLIAADVPYGDASGKGNYRSEGDIPRNESLDSALGDSDDEACVLALLELGHSC DRTEESLEVELPLPRSQSTSKANVRNFGRSLLAGYCATYMPDLVLHGTSSDEKLKQCLAADLVHTVHHPV LDEPIAEAVCIIADTDKWTVQVATSQRKVTDTMKLGQDVLVSSQVSSLLQSILQLYKLHLPADFCIMHLE DRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESNDLPLLTAIASTHSPYVAQILL SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	122.5 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001156471
Locus ID	329679
UniProt ID	Q80TD3
Refseq Size	7095
Cytogenetics	3 E3
Refseq ORF	3324
Synonyms	D630023B12Rik; mKIAA1450
Summary	Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1 (By similarity). May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (PubMed:19137017).[UniProtKB/Swiss-Prot Function]

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