Rragd (NM_027491) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR216840 representing NM_027491 Red=Cloning site Green=Tags(s) MSQVLGKPQPQGEDGGEDEEEDELVGLAGYEDGPESSDAELDSGPEEGVLDFSDPFSTEVKPRILLMGLR RSGKSSIQKVVFHKMSPSETLFLESTNRICREDVSNSSFVNFQIWDFPGQIDFFDPTFDYEMIFRGTGAL IFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADAGLEK IHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSTPVDMQ TYELCCDMIDVVIDISCIYGLKEDGAGAPYDKDSTAIIKLNNTTVLYLKEVTKFLALVCFVREESFERKG LIDYNFHCFRKAIHEVFEVRMKMVKSRKAQSRLPKKTGATPNGTPRVLL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	45.6 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_081767
Locus ID	52187
UniProt ID	Q7TT45
Refseq Size	5047
Cytogenetics	4 14.57 cM
Refseq ORF	1197
Synonyms	5730543C08Rik; AI467523; C030003H22Rik; D4Ertd174e
Summary	Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids (By similarity).[UniProtKB/Swiss-Prot Function]

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