Tbc1d2 (NM_198664) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR212945 representing NM_198664 Red=Cloning site Green=Tags(s) MEDAPERTPSSSESTQPPGLAREPEVVSPGDSEGCARPLDTVPKKLCGYLSKFGGKGPIKGWKCRWFFYD ERKCHLYYSRTAQDANPLDSIDLSSAVFDCKADAEEEGTFEIKTPSRVITLKAATKQAMLYWLQQLQMKR WEFHNSPPALPATPAAALAENGPTLHLKLEQEEAELEEFLCPVKTPTGLVGAAAALQPVPAVPSALQNIS LKHLGTEIQNTMHNIRGNKQAQAAAHGPLVEDSPQGGEPQSGEQPSISDPSLPEKEPEDPAKSAPRSSVP SGPTQKPKRQSNTFPFFSDGLARSRTAQEKVAALEQQVLMLTKELKSQKELVIILHKALEAAQQEKRASS AYLAATEDRDRLELVRHKVRQIAELNQRVEALEQGRERLAHEAGLREQQVQALQQHVQLLMDKNHAKQQV ICKLTQKLTEDLAQPADATNGDFLSQQERMEHLKDDMEAYRTQNRFLNSEIHQVTKIWRKVAEKEKALLT KCAYLQARNCQVESKYLAGLRRLQEAAGAEAGDFPELLQQLIQEALQWEAGEADSVGLSPVSEYDDYGFL TVPDYEMEDLKLLAKIQALEVRSHHLLAHEAVERPLRDRWATLTELTPSAELKQLLRAGVPREHRPRVWR WLVHRRVRHLQAPGCYQELLARGRACEHPAARQIELDLNRTFPTNKHFTCPTSSFPDKLRRVLLAFSWQN PTIGYCQGLNRLAAIALLVLEDEESAFWCLVAIVETILPAEYYSKTLTASQVDQRVLQDLLSEKLPRLTA HLGQHRVDLSLITFNWFLVVFADSLISDILLRVWDAFLYEGTKVVFRYALAIFKYNEEAILQLQDSLEIY QYLRFFTKTICDSRKLMSIAFNDMNPFPMKQLRQLRAAHRERLEAELRELELLKVEYLQRRASLGRAPPE GCVSEDEGEGDS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	104.3 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_941066
Locus ID	381605
UniProt ID	B1AVH7
Refseq Size	4305
Cytogenetics	4 B1
Refseq ORF	2766
Synonyms	A630005A06Rik; BC022630; Gm1037; PARIS-1; PARIS1
Summary	Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion (By similarity).[UniProtKB/Swiss-Prot Function]

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