Gtf2ird1 (NM_001081465) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR211520 representing NM_001081465 Red=Cloning site Green=Tags(s) MALLGKHCDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKG RVFLNTRKELQSDFLRFCRGPLWNDPEAGHPKKVQRCEGGGRSLPRSSLEQCSDVYLLQKMVEEVFDVLY SEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQD TKALVEMNGISLLPKGSRDCGLHGQASKVAPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLT PSDLGMGWPVPEPHVPSTQDFSDCCGQTPAGPAGPLIQNVHASKRILFSIVHDKSEKWDPFIKEMEDINT LRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIH FIIKRMFDERIFTGNKFTKDPMKLEPASPPEDTSTEVCRDSMLDLAGTAWSDMSSVSEDCGPGTSGEIAM LRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWSEERPAEESPGD VIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEAS NSIQFVIKRPELLTDGVKEPVLDTQERDSWDRLVDETPKRQGLQENYNTRLSRIDIANTLREQVQDLFNK KYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLI PKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTY DIHRLEKILKAREHVRMVIINQLQPFAEVCNDPKVPEEDDSNKLGKKVILREQVKELFNEKYGEALGLNR PVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFGDVCNNAKVPA KDNIPKRKRKRVSEGNSVSSSSSSSSSSSNPESVASTNQISLVQWPVYMVDYSGLNVQLPGPLDY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	117.6 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001074934
Locus ID	57080
UniProt ID	Q6PD35, Q5XJY7, Q8BP10
Refseq Size	3480
Cytogenetics	5 74.55 cM
Refseq ORF	3135
Synonyms	1700012P16Rik; BEN; Cream1; ESTM9; Gtf2il; GTF3; MusTRD1; Tg(Alb1-Myc)166.8Sst; WBSCR11; X83320
Summary	May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8.[UniProtKB/Swiss-Prot Function]

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