Ints5 (NM_176843) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR211457 representing NM_176843 Red=Cloning site Green=Tags(s) MSALCDPPGAPGPPGPAPATHGPAPLSAQELSQEIKAFLTGVDPILGHQLSAREHARCGLLLLRSLPPAR AAVLDHLRGVFDESVRAHLAALEESPVAGPPHLRPPPPSHVPTGGPGLEDVVHEVQQVLCEFIRANPKAW APVISAWSIDLMGQLSSTYSGQHQRVPHATGSLNELLQLWMGCRATRTLMDIYVQCLSALIGSCPDACVD ALLDTSVQHSPHFDWVVAHIGSSFPGTIISRVLSCGLKDFCVHSGAGGGASACGNSSQPPSTDPFPGSPA IPGEKRVPKIASVVGILGHLASRHGDSIRRELLRMFHDSLAGGSGGRNGEPSLQATVPFLLQLAVMSPAL LGTVSGELVDCLKPPAVLSQLQQHLQGFPREELDNMLNLAVHLVSQASGTGAYRLLQFLVDTAMPASVIT TQGLAVPDTVREACDRLIQLLLLHLQKLVHHRGGSPGEGVLGPPPPPRPVPFLDALRNHVGELCGETLRL ERKRFLWQHQLLGLLSVYTRPSCGPEALGHLLSRARSPEELSLATQLYAGLVVSLSGLLPLAFRSCLARV HAGTLQPPFTARFLRNLALLVGWEQQGGEGPSALGARFGESASAHLADLAPLLLHPEEEVAEAAASLLAI CPFPSEALSPSQLLGLVRAGVHHFFSSLRLHGPPGVASASQLLTRLSQTSPAGLKAVLQLLVEGALHRGN TELFGGEMDGDNETLSIVSTPLASASLLDINRRHTAAVPGPGGIWSVFHAGVIGRGLKPPKIVQSRNHQE VIYNTQSLVSLLVHCCSASGNSEREGCWGAPTLSPEAAKAVAVTLVESVCPDAAGAELAWPPEDHARATV ERDLRIGRRFREQPLLFELLKLVAAAPPALCYCSVLLRGLLAALLSHWEASRHPDTTHSPWHLEASCILV AVMAEGSLLPPALGNMHEVFSQLAPFEVRLLLLSVWGFLREHGPLPQKFIFQSERGRFIRDFAREGGAEG GPHLSVLHSVLHRNIDRLGLFSGRFQAPPPSTLLRQGT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	108.3 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_789813
Locus ID	109077
UniProt ID	Q8CHT3
Refseq Size	3294
Cytogenetics	19 A
Refseq ORF	3054
Synonyms	1110055N21Rik; mKIAA1698
Summary	Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.[UniProtKB/Swiss-Prot Function]

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