Plekhg6 (NM_198604) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR210656 representing NM_198604 Red=Cloning site Green=Tags(s) MQAFGPPNEGPLQGLVASRIETYGGRHQTSAHSTAGNLFPRGGPGVDPSRRRLQHYVPFAKGSGQTRGMS PLVLREPDPEKRHGSYFGVGPPHSPKLKEVTRAHELEIRLHTFSMFGMPRLPPEDRRHWEIGEGGDSALT MEKSWKELVLEHKEMNRQLCHQQEALWELLTTELIYLRKLKIMTDLLAAGLLNLQRVGLLTEVSAETLFG NVPNLIRAHRRFWEEVLQPILEDTRTSGQPLDPVSLQNGFLTFGQRFQPYVQYCLRVKQTMAYAREQQDT NPLFHTFVQWCEKHKRSGRQTLGDLLIKPHQRITKYPLLLQAVRKRSPEPRAQEALNAMIEAVESFLRHI NGQVRQGEEQESLMAVAQRIGPYEVLEPSSEEVEKNLRPFSTLDLMTPVLGVAPEYTRQLLLEGPVRVKE GREGKMDVYLFLFSDVLLVTKPQRKADRAKVIRPPLMLEKLVCRPLRDPNSFLLIHLTEFQCVSSALTVH CPSSTERARWLEKTQHAQTTLQKLKGEQYIQQKRELLALYRNQGTESPSTRPSTPSPSPEDSQSSAEGRT LEFAIIPRLVVTEDTDEDTPSMPDDASDSGYGTLIPSSPKDSHSPLNRLRSKALRRDPRLTFSTLELRDV PLRPQPPDPQAPQRRSAPELPEGILRGGSLPRRAPPIWSEEEDETLASGNVVVETLHRAQRRSPLPHSPT HTDSAGESPWESSDEDEGLLSPELRPRSLREDMLREIREELANQRIDGASEPEPGNGKPRRLTLAQLQRM RVPHIIQLDTPLSTSEV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	89.1 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_941006
Locus ID	213522
UniProt ID	Q8R0J1
Refseq Size	3019
Cytogenetics	6 F3
Refseq ORF	2361
Synonyms	BC026778; Gm155
Summary	Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis (By similarity).[UniProtKB/Swiss-Prot Function]

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