Pus10 (NM_028304) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR208455 protein sequence Red=Cloning site Green=Tags(s) MLPLTEENKHVAQLLFSSGTCPRCILRFCGVDLPAPYKHPSKELLNELQKFLEPEKPELILEAPNPPLKK IRLHEDGIDNLSEDGKEGVSVTEDESMAEKPSKLRVCNVCLGILQEFCEKGFITKVCQKVEASGFEFTSV VLSVSFPPQLSVREHAAWLLVKQEMGKQSLSLGRNDVVQLKEAYKWITHPLFSEELGVPTDGKSLFEVSV VFAHPETAEDCHFLGEVCRDCFKPAKNKQSVFTRMAVLKALSKIKEEDFLGQFPCPPNSPKTVCTVLEVE CTHGAVFVAGRYNKYSRNLPQTPWIIDGERKMESSVEELISDHLLAVFRAESFNFSSSGREDVDVRTLGN GRPFAVELLNPHRVHFTSQEMKELQQTINKSSDKIQVRDLQLVTREAIGHMKEGEEEKTKTYSALIWTNR AIQKKDIGFLDDLKDLKIDQKTPLRVLHRRPLAVRTRAIHSMKTHYLDEHHFRLHLKTQAGTYIKEFVHG DFGRTKPNLGSLMNVTADILELDVESVDVDWPPALDD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	59.7 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_082580
Locus ID	74467
UniProt ID	Q9D3U0
Refseq Size	3590
Cytogenetics	11
Refseq ORF	1581
Synonyms	2810013G11Rik; 4933435A13Rik; AU014648; C77560; Ccdc139
Summary	Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death (By similarity).[UniProtKB/Swiss-Prot Function]

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