Tti2 (NM_001112729) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR208229 protein sequence Red=Cloning site Green=Tags(s) MKLDSAEEKSGVGCSLPAEGSPPALEPAFSKILNRLSRPKSSGQGGARNAALKDLGALIEAAEGDRFFEG SGSGGSLRGMPEILGQVVRALEKFAAPEEKADGVEEPPEVPEKATEVGSLFLKLLGKVEAAKSSPDCPAW KTGLRHMSGPVYIFAITHRLKQPWTSPASQHVAGEVLSLLLRVTECSSVAGFLCGENEDDRGRFAVVLGL LKPHLNKETWKKNPAVKHVFSWTLQQVTQPWLNQHLEKILPPSLLISDDYQTENKILGVQCLHHIVVTVP AADLLQYNRAQVLYHALFNHLYMPEHHLIQAVLLCLLDLFPVLEKALHWKGDTARVTTHCHEVLQLILTH MEPEHRLLLRRTYARHLPAFVKRLGILTVRHLKRLEQVILGYLEVYDEPEDETRLKILETLKLVMQYTWP RIPCRVVVLLKALLKLICDISRDTIPTTEAAKSTMLQEATDCLILLDHCSQGQVKGLLAKIAVSCEDSTV VSCIRKVQQGSADSPGDDTEGD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	56.7 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
Locus ID	234138
UniProt ID	Q8BGV4
Refseq Size	5059
Cytogenetics	8 A3
Refseq ORF	1536
Synonyms	MGC28346
Summary	Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs (By similarity).[UniProtKB/Swiss-Prot Function]

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