Amer2 (NM_001164705) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR207536 protein sequence Red=Cloning site Green=Tags(s) MPSIFGVKNKGDGKSSGPTGMVRSRTHDGLAEVLVLEGSKKEEPPGGSDHSGARPIPGPPKPSGPGLGSL ASSSVAKSHSFFSLLKKNGRSETGKGDHAEASKAGGKQKRGLKGIFSSMRWHRRDKRGKEEEEKAVRAAG PGNLVLPGSLTASLECVKEEPPRAARRPDSPGQDASRHAAGCGDIIADPEEEAGPSCDKHVPGPGKPVLS KKNASVVAYQGGGEEMASPDQVDDTYLPEFWDMLSQTEDQGQGTQEGAAKAATASDIKLAPETSSDTRCG EAAKDMSSVKRRRLHRIPIESQQKEEPKHPEKEHQEGVPNSDEGYWDSTTPGPEEESISNSSSSKKVVIP RDSDSGDALCDLYVEPEASPATLPATEDPPCLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLSNLP SSHPVVHQQPARSEVPRTKIPVSKVLVRRVSNRGLAGTTIRAAACHDSAKKL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	50 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001158177
Locus ID	72125
UniProt ID	Q8CCJ4
Refseq Size	2340
Cytogenetics	14 D1
Refseq ORF	1416
Synonyms	2600011E07Rik; Fam123a
Summary	Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex (By similarity).[UniProtKB/Swiss-Prot Function]

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