Zfyve19 (NM_028054) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR206077 protein sequence Red=Cloning site Green=Tags(s) MESRCYGCAVKFTLFKKEYGCKNCGRAFCNGCLSFSALVPRAGNTQQKVCKQCHTILTRGSSDSASKWSP PQNYKKRVAALEAKKKSSTSQSQGLTHKDQAIAERLARLRQENKPKSVPSQAEIEARLAALKDEVQGPIP STQEMEDRLAALQGRVPPSHTVRLAHQAPDTRTQAQQTQDLLTQLTAEVAIDENCQPRASASLQNDLNKG AARSQRTNSQGQASQSLEAEKYKLLAEAAVELQEENTRQERILALAKRLAVLKGQDPSRVTLQDYHLPDS DEDEETAIQRVMQQLTEEAALDEASGFNIPEKPAPGSRAQPCKAEMEGPQAEEEELPWCCICNEDATLRC AGCDGDLYCARCFREGHDNFDLKEHQTSPYHPRRPCQEH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	43.2 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_082330
Locus ID	72008
UniProt ID	Q9DAZ9
Refseq Size	1941
Cytogenetics	2 E5
Refseq ORF	1167
Synonyms	1500041L05Rik; ANCHR
Summary	Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission (By similarity).[UniProtKB/Swiss-Prot Function]

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