Gkap1 (NM_019832) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR205634 representing NM_019832 Red=Cloning site Green=Tags(s) MASAVLSSVLTTASRFALLQVDSGSGSDSEPGKGKGRSNGKSQTLGNKATSNEKKREKRRKKKEQQQSEA NELRNLAFKKIPQKSSHSICNVQHELSSPNPAQKESREENWQEWRQKDEQLTSEMFEADLEKALLLSKLE YEEHKQDYENAETASTQTKGINKKDKRKNHQGKDKPVTVSLKDFQCEDHISKKAEESNSAQTLSHDGGFF NRLEDDVHKILIREKRREQLTEHNGTDNSPAPEHNQEVGLKDGRIERLKLELERKDAEIQKLKAVITQWE AKYKEVKARNGQLLKMLQEGEMKDKAEILLQVDESQSIKNELTVQVSSLHAALEQERSKVKVLQAELAKY QGGRKGKRNFEPDHCR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	42.2 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_062806
Locus ID	56278
UniProt ID	Q9JMB0
Refseq Size	1547
Cytogenetics	13 30.97 cM
Refseq ORF	1098
Synonyms	42kDa; 4933400B15Rik; D13Ertd340e; Gkap42
Summary	Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.[UniProtKB/Swiss-Prot Function]

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