MICA (NM_001177519) Human Recombinant Protein
CAT＃: TP329900
Purified recombinant protein of Homo sapiens MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801), 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC229900 representing NM_001177519
Red=Cloning site Green=Tags(s) MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYDRQKCRAKPQG QWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELF LSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLESGVVLRRTVPPMVN VTRSEASEGNITVTCRASSFYPRNIILTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRF TCYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAGCCYFCYYYFLCPLL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 38.3 |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | NULL or Add: Recombinant proteins was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_001170990 |
| Locus ID | 100507436 |
| UniProt ID | Q96QC4 |
| Cytogenetics | 6p21.33 |
| Refseq ORF | 996 |
| Synonyms | MIC-A; PERB11.1 |
| Summary | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400095 | MICA HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC432900 | MICA HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400095 | Transient overexpression lysate of MHC class I polypeptide-related sequence A (MICA) |
CNY 3080.00 |
|
| LY432900 | Transient overexpression lysate of MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801) |
CNY 3080.00 |
|
| PH304447 | MICA MS Standard C13 and N15-labeled recombinant protein (NP_000238) |
CNY 19520.00 |
|
| TP304447 | Recombinant protein of human MHC class I polypeptide-related sequence A (MICA), 20 µg |
CNY 2900.00 |
|
| TP720672 | Purified recombinant protein of Human MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*001) |
CNY 1800.00 |
|
| TP720954 | Purified recombinant protein of Human MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*001) |
CNY 1800.00 |
