FAM89B (NM_001098785) Human Recombinant Protein
CAT＃: TP318225
Recombinant protein of human family with sequence similarity 89, member B (FAM89B), transcript variant 1, 20 µg
View other "FAM89B" proteins (7)
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC218225 representing NM_001098785
Red=Cloning site Green=Tags(s) MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAG AANAGPAAGPRRPVNLDSALAALRKEMVGLRQLDMSLLCQLWGLYESIQDYKHLCQDLSFCQDLSSSLHS DSSYPPDAGLSDDEEPPDASLPPDPPPLTVPQTHNARDQWLQDAFHISL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 20 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_001092255 |
| Locus ID | 23625 |
| UniProt ID | Q8N5H3 |
| Refseq Size | 1467 |
| Cytogenetics | 11q13.1 |
| Refseq ORF | 567 |
| Synonyms | LRAP25; MTVR; MTVR1 |
| Summary | Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta. Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation.[UniProtKB/Swiss-Prot Function] |
| Protein Families | Druggable Genome |
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| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC407290 | FAM89B HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC420673 | FAM89B HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC420674 | FAM89B HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY407290 | Transient overexpression lysate of family with sequence similarity 89, member B (FAM89B), transcript variant 2 |
CNY 3080.00 |
|
| LY420673 | Transient overexpression lysate of family with sequence similarity 89, member B (FAM89B), transcript variant 3 |
CNY 3080.00 |
|
| LY420674 | Transient overexpression lysate of family with sequence similarity 89, member B (FAM89B), transcript variant 1 |
CNY 3080.00 |
|
| PH318225 | FAM89B MS Standard C13 and N15-labeled recombinant protein (NP_001092255) |
CNY 19520.00 |
