IL1RA (IL1RN) (NM_000577) Human Recombinant Protein
CAT＃: TP312460
Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3, 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC212460 protein sequence
Red=Cloning site Green=Tags(s) MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGG KMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSL TNMPDEGVMVTKFYFQEDE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 17.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_000568 |
| Locus ID | 3557 |
| UniProt ID | P18510 |
| Refseq Size | 1802 |
| Cytogenetics | 2q14.1 |
| Refseq ORF | 477 |
| Synonyms | DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4 |
| Summary | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020] |
| Protein Families | Druggable Genome, Secreted Protein |
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| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403570 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC403571 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC406440 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC424628 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY403570 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 1 |
CNY 3080.00 |
|
| LY403571 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 4 |
CNY 3080.00 |
|
| LY406440 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 2 |
CNY 3080.00 |
|
| LY424628 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 3 |
CNY 3080.00 |
|
| PH302447 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776215) |
CNY 14250.00 |
|
| PH312460 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_000568) |
CNY 19520.00 |
|
| PH318518 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776214) |
CNY 19520.00 |
|
| TP302447 | Purified recombinant protein of Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 4, 20 µg |
CNY 2900.00 |
|
| TP318518 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 1, 20 µg |
CNY 2900.00 |
|
| TP720025 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3 |
CNY 1800.00 |
|
| TP760033 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
CNY 2040.00 |
