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ITM2C (NM_001012514) Human Recombinant Protein
CAT＃: TP308687
Recombinant protein of human integral membrane protein 2C (ITM2C), transcript variant 3, 20 µg
View other "ITM2C" proteins (8)
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC208687 protein sequence
Red=Cloning site Green=Tags(s) MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPARLARDNFFRCGVLYEDSLSSQVRTQMELEED VKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFWELLMNVK RGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRINKRGAKNCNAIRHFENTF VVETLICGVV TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 24.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_001012532 |
| Locus ID | 81618 |
| UniProt ID | Q9NQX7 |
| Refseq Size | 1974 |
| Cytogenetics | 2q37.1 |
| Refseq ORF | 660 |
| Synonyms | BRI3; BRICD2C; E25; E25C; ITM3 |
| Summary | Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).[UniProtKB/Swiss-Prot Function] |
| Protein Families | Transmembrane |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403097 | ITM2C HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC422880 | ITM2C HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC422882 | ITM2C HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY403097 | Transient overexpression lysate of integral membrane protein 2C (ITM2C), transcript variant 1 |
CNY 3,080.00 |
|
| LY422880 | Transient overexpression lysate of integral membrane protein 2C (ITM2C), transcript variant 3 |
CNY 3,080.00 |
|
| LY422882 | Transient overexpression lysate of integral membrane protein 2C (ITM2C), transcript variant 2 |
CNY 3,080.00 |
|
| PH308687 | ITM2C MS Standard C13 and N15-labeled recombinant protein (NP_001012532) |
CNY 19,520.00 |
|
| TP761803 | Purified recombinant protein of Human integral membrane protein 2C (ITM2C), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug |
CNY 2,040.00 |
