GATA3 (NM_002051) Human Recombinant Protein
CAT#: TP301618
Recombinant protein of human GATA binding protein 3 (GATA3), transcript variant 2, 20 µg
View other "GATA3" proteins (8)
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CNY 2900.00
CNY 6650.00
| Cited in 2 publications. | 
                                                
                                                
                                                
                                                    CNY 1999.00 
                                                    
                                                    CNY 2700.00
                                                
                                            
CNY 600.00
Specifications
| Product Data | |
| Species | Human | 
| Expression Host | HEK293T | 
| Expression cDNA Clone or AA Sequence | >RC201618 protein sequence Red=Cloning site Green=Tags(s) MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHVPPYYGNSVRA TVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSS LSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGG ASSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGT GHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHN INRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTP TPMHPPSSLSFGPHHPSSMVTAMG TRTRPLEQKLISEEDLAANDILDYKDDDDKV | 
| Tag | C-Myc/DDK | 
| Predicted MW | 47.7 kDa | 
| Concentration | >0.05 µg/µL as determined by microplate BCA method | 
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining | 
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol | 
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. | 
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. | 
| Storage | Store at -80°C. | 
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. | 
| Bioactivity | GATA3 Activity Verified in a DNA-binding Assay: DNA binding activity of GATA3 as a function of protein concentration. Sensitivity to competitor oligonucleotide demonstrates specificity of protein-DNA binding. EMSA assay (PMID: 26216189) | 
| Reference Data | |
| RefSeq | NP_002042 | 
| Locus ID | 2625 | 
| UniProt ID | P23771 | 
| Refseq Size | 3067 | 
| Cytogenetics | 10p14 | 
| Refseq ORF | 1332 | 
| Synonyms | HDR; HDRS | 
| Summary | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009] | 
| Protein Families | Adult stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors | 
Citations (2)
| The use of this Proteins has been cited in the following citations: | 
|---|
| Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia
                                                ,Belver, L;Yang, AY;Albero, R;Herranz, D;Brundu, FG;Quinn, SA;Perez-Duran, P;Alvarez, S;Gianni, F;Rashkovan, M;Gurung, D;Rocha, PP;Raviram, R;Reglero, C;Cortes, JR;Cooke, AJ;Wendorff, AA;Cordo, V;Meijerink, JP;Rabadan, R;Ferrando, AA;,
                                                Cancer Discov
                                                ,PubMed ID 31519704
                                                [GATA3] | 
| Transactivation of human osteoprotegerin promoter by GATA-3
                                                ,Kao, SY;Stankovic, KM;,
                                                Sci Rep
                                                ,PubMed ID 26216189
                                                [GATA3] | 
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Other Versions
| SKU | Description | Size | Price | 
|---|---|---|---|
| LC400759 | GATA3 HEK293T cell transient overexpression lysate (as WB positive control) | CNY 900.00 | |
| LC424146 | GATA3 HEK293T cell transient overexpression lysate (as WB positive control) | CNY 1470.00 | |
| LY400759 | Transient overexpression lysate of GATA binding protein 3 (GATA3), transcript variant 2 | CNY 3080.00 | |
| LY424146 | Transient overexpression lysate of GATA binding protein 3 (GATA3), transcript variant 1 | CNY 4840.00 | |
| PH301618 | GATA3 MS Standard C13 and N15-labeled recombinant protein (NP_002042) | CNY 19520.00 | |
| TP761574 | Purified recombinant protein of Human GATA binding protein 3 (GATA3), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug | CNY 2040.00 | |
| TP762348 | Purified recombinant protein of Human GATA binding protein 3 (GATA3), transcript variant 1, Pro189-Ser201(8 reapeat regions linked with GGGGS), with N-terminal His tag, expressed in E.coli, 50ug | CNY 1950.00 | |
| TP762449 | Purified recombinant protein of Human GATA binding protein 3 (GATA3), transcript variant 1, Met1-Thr156, with N-terminal His tag, expressed in E.coli, 50ug | CNY 1950.00 | 


 
                         
                            

 
        