Myostatin (His-tagged Fusion Protein) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDPSSRSAVR SRRDFGLDCD EHSTESRCCR YPLTVDFEAF GWDWIIAPKR YKANYCSGEC EFVFLQKYPH THLVHQANPR GSAGPCCTPT KMSPINMLYF NGKEQIIYGK IPAMVVDRCG CS
Tag	His-tag
Concentration	lot specific
Purity	>95% pure.
Buffer	Presentation State: Purified State: Lyophilized (0.4 µm filtered) purified protein. Buffer System: 0.05 M Acetate buffer, pH 4.5
Preparation	Lyophilized (0.4 µm filtered) purified protein.
Applications	ELISA. Western Blot.
Protein Description	N-terminal His-tag including the spacer 43AA (highlighted). The AA sequence of the human myostatin part of the fusion protein.
Note	Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Storage	Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after two weeks at 4°C. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_005250
Locus ID	2660
UniProt ID	O14793
Cytogenetics	2q32.2
Synonyms	MSTN, GDF8, GDF-8, Growth differentiation factor 8
Summary	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
Protein Families	ELISA. Western Blot.

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