LYVE-1 Mouse Protein

Specifications

Product Data
Species	Mouse
Expression Host	Insect
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) ADLVQDLSIS TCRIMGVALV GRNKNPQMNF TEANEACKML GLTLASRDQV ESAQKSGFET CSYGWVGEQF SVIPRIFSNP RCGKNGKGVL IWNAPSSQKF KAYCHNSSDT WVNSCIPEIV TTFYPVLDTQ TPATEFSVSS SAYLASSPDS TTPVSATTRA PPLTSMARKT KKICITEVYT EPITMATETE AFVASGAAFK NEAAGHHHHHH
Predicted MW	45 kDa
Purity	>95% by SDS-PAGE and visualised by silver stain
Buffer	Presentation State: Purified State: Lyophilized protein Buffer System: PBS Stabilizer: None
Preparation	Lyophilized protein
Protein Description	Recombinant Mouse Soluble LYVE-1-His. A DNA sequence encoding the extracellular domain of mouse LYVE-1 (Met1 - Gly228) was fused to a C-terminal His -tag (6xHis) and expressed in insect cells. Based on N-terminal sequence analysis, the primary structure of recombinant mature sLYVE-1 starts at Ala24. Result by N-terminal sequencing: ADLVQDLS Length: 211 amino acids.
Storage	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Endotoxin	< 0.1 ng per µg of VEGF-C
Reference Data
RefSeq	NP_444477
Locus ID	114332
UniProt ID	Q8BHC0
Cytogenetics	7 E3
Synonyms	LYVE1, CRSBP-1, CRSBP1, HAR, XLKD1
Summary	Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.[UniProtKB/Swiss-Prot Function]

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