Placenta growth factor / PGF (Isoform PlGF-2) Human Protein

Specifications

Product Data
Species	Human
Expression Host	Insect
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR
Predicted MW	~ 45 kDa
Purity	>90% pure by SDS-PAGE and visualised by silver stain.
Buffer	Presentation State: Purified State: Lyophilized purified protein. Buffer System: 50 mM Acetic Acid with BSA (50-fold) as stabilizer.
Preparation	Lyophilized purified protein.
Protein Description	Recombinant Human Placenta Growth Factor-2 / PIGF-2. Result by N-terminal sequencing: LPAVPPQQWA Length (aa): 152
Storage	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Bioactivity	Biological: Measured by its ability to bind to immobilized recombinant Human sFlt-1 in a functional ELISA. Recombinant human PlGF-2 can bind to immobilized rh sFlt-1 (100 ng/well) with a linear range at 0.5-10 ng/ml.
Endotoxin	0.1 ng per µg of PIGF-2
Reference Data
RefSeq	NP_001193941
Locus ID	5228
UniProt ID	P49763
Cytogenetics	14q24.3
Synonyms	PGFL, PLGF, PlGF
Summary	This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Bladder cancer, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma

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