SUMO3 / SMT3A (1-92, His-Tag) Human Protein
CNY 14920.00
货期*
详询
规格
| Cited in 1 publication. |
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
|
| Tag | His-Tag |
| Predicted MW | 12.6 kDa (112aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher) |
| Concentration | 1mg/ml (determined by BCA assay) |
| Purity | > 95% by SDS-PAGE |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT |
| Preparation | Liquid purified protein |
| Applications | SDS-PAGE |
| Protein Description | Recombinant human SUMO3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Reference Data | |
| RefSeq | NP_008867 |
| Locus ID | 6612 |
| UniProt ID | P55854 |
| Cytogenetics | 21q22.3 |
| Synonyms | Small ubiquitin-related modifier 3, SMT3A, SMT3H1, SuMO-3, sumo3, sumo 3 |
| Summary | This gene encodes a member of the small ubiquitin-related modifier (SUMO) family of eukaryotic proteins. The encoded protein is covalently conjugated to other proteins via a post-translation modification known as sumoylation. Sumoylation may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Alternatively spliced transcript variants encoding distinct proteins have been described. [provided by RefSeq, Feb 2014] |
| Protein Families | Druggable Genome |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
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Cathepsin E generates a sumoylated intracellular fragment of the cell adhesion molecule L1 to promote neuronal and Schwann cell migration as well as myelination.
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Journal of neurochemistry
,PubMed ID 24118054
[SUMO3]
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