TARM1 (NM_001135686) Human Mass Spec Standard

Specifications

Product Data
Description	TARM1 MS Standard C13 and N15-labeled recombinant protein (NP_001129158)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC226937
Predicted MW	29.3 kDa
Protein Sequence	Sequence Link (showhide) >RC226937 representing NM_001135686 Red=Cloning site Green=Tags(s) MIPKLLSLLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESP KPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGG RVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSPFWASEP SDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAWYSRNVSPGESEAFKPE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001129158
RefSeq ORF	813
Synonyms	OLT-2
Locus ID	441864
Cytogenetics	19q13.42
Summary	May act as receptor (By similarity). Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface (PubMed:26311901). Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity).[UniProtKB/Swiss-Prot Function]

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