Nkx2.6 (NKX2-6) (NM_001136271) Human Mass Spec Standard

Specifications

Product Data
Description	NKX2 MS Standard C13 and N15-labeled recombinant protein (NP_001129743)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC226770
Predicted MW	23.1 kDa
Protein Sequence	Sequence Link (showhide) >RC226770 representing NM_001136271 Red=Cloning site Green=Tags(s) MDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFK QQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLG PGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLA ATLQGVRAW TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001129743
RefSeq ORF	657
Synonyms	CSX2; CTHM; NKX2F; NKX4-2
Locus ID	137814
Cytogenetics	8p21.2
Summary	This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011]

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